Time and spatial distribution characters on multiple infections of hand, foot and mouth disease in Liaocheng City

Objective Using spatial autocorrelation analysis to explore the hot spot areas in the spatial distribution of hand,foot and mouth disease multiple infection,explore the characteristics of geographic epidemics and reveal the epidemic law of multiple infection of hand,foot and mouth disease in L:iaopcheng city,so as to provide scientific basis for the prevention and treatment of hand,foot and mouth disease.Methods Excel 2003 and Access 2003 software management database were used to screen multiple infection cases of hand,foot and mouth disease in the China management system of disease surveillance reports from 2008 to 2011.ArcGIS9.3 software was used as data management and analysis platform to study the spatial distribution rules and characteristics of foot and mouth disease multiple infection cases,and spatial statistics module was used for overall spatial autocorrelation analysis and local hot spot analysis,and comprehensively respond to the spatial distribution of disease characteristics.Results The incidence rate of hand,foot and mouth disease multiple infection was 17.8 ‰ in Liaocheng city,2008 - 2011,and the spatial distribution was mostly concentrated in the areas with higher average incidence and larger population migration; different types of enteroviruses and the same enterovirus could cause multiple infections,and 97％ were different types of virus infection; the incidence of multiple infection in the temporal distribution was consistent with the total incidence,more in males than in females,those under 3 years of age accounted for 89.6％,mainly scattered-living children,those above 3 years old were mainly children in childcare institutions; overall spatial autocorrelation Moran's I =0.28,u =4.91,P ＜0.01 generalized G statistic G =0.005,u (G) =5.45,P ＜0.01,the use of local statistics derived the distribution of diseases aggregation,the hot areas were mainly concentrated in Chiping county and Dongchangfu district.Conclusion s The spatial distribution of HFMD in Liaocheng city was not random but cluster.strengthening the control measures in hot spots is very importance.