What question did this study set out to answer?

To evaluate the performance of the BioFire FilmArray Pneumonia Panel compared to routine diagnostics and determine its potential impact on antimicrobial stewardship in hospitalized adults with lower respiratory tract infections.

April 28, 2020Journal of Clinical MicrobiologyOpen Access

Practical Comparison of the BioFire FilmArray Pneumonia Panel to Routine Diagnostic Methods and Potential Impact on Antimicrobial Stewardship in Adult Hospitalized Patients with Lower Respiratory Tract Infections

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Authors

BBBlake W. BuchanMedical College of Wisconsin SWSam WindhamUniversity of Kansas Medical Center JBJoan‐Miquel Balada‐LlasatThe Ohio State University

Discussion

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Implication

Diagnostic evaluation reveals potential antibiotic optimization in hospitalized lower respiratory infection patients, suggesting significant gains for antimicrobial stewardship.

Key Points

To evaluate the performance of the BioFire FilmArray Pneumonia Panel compared to routine diagnostics and determine its potential impact on antimicrobial stewardship in hospitalized adults with lower respiratory tract infections.
Tested respiratory specimens from hospitalized adult patients with lower respiratory tract infections using the BioFire FilmArray Pneumonia (PN) panel.
Conducted a retrospective medical record review of clinically prescribed antibiotics to model potential adjustments, de-escalation, and days of therapy saved.
Viral targets were detected in 17.7% of specimens, with 39.1% of those detected alongside a bacterial target.
Medical record analysis indicated potential antibiotic adjustment in 70.7% of patients, with discontinuation or de-escalation feasible in 48.2%.
Implementation of panel-guided therapy demonstrated an estimated average reduction of 6.2 antibiotic days per patient.

Cite This Study

Buchan et al. (2020) studied this question.

synapsesocial.com/papers/6a0230ae8b14fde368dcf2a5 https://doi.org/10.1128/jcm.00135-20

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Implication

Diagnostic evaluation reveals potential antibiotic optimization in hospitalized lower respiratory infection patients, suggesting significant gains for antimicrobial stewardship.

Practical Comparison of the BioFire FilmArray Pneumonia Panel to Routine Diagnostic Methods and Potential Impact on Antimicrobial Stewardship in Adult Hospitalized Patients with Lower Respiratory Tract Infections

Discussion

Member takes

Implication

Key Points

Cite This Study

Practical Comparison of the BioFire FilmArray Pneumonia Panel to Routine Diagnostic Methods and Potential Impact on Antimicrobial Stewardship in Adult Hospitalized Patients with Lower Respiratory Tract Infections

Discussion

Member takes

Implication

Key Points

Cite This Study

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