Interventional study reveals distinct cortical excitability changes across stimulation intervals in individuals, suggesting session spacing regulates brain plasticity.
OBJECTIVE: The study aims to investigate the after-effect of three sessions of intermittent theta-burst stimulation (iTBS) on motor cortical excitability. The iTBS was induced over the primary motor cortex (M1) at different time intervals. METHODS: 30). As washout period, each visit is separated by at least 7 days. We measured the motor cortical excitability changes and intracortical inhibition. RESULTS: 30 exhibited the longer effect and highest percentage of individuals with enhanced cortical excitability. CONCLUSION: The results suggest that aiTBS protocols at different time intervals result in different motor cortical excitability after-effects.
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Yu et al. (2020) studied this question.
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