What question did this study set out to answer?

Identify key analytical methods, software tools, databases, and continuing challenges for integrating multiple omics datasets using principles from metabolomics research.

April 18, 2019MetabolitesOpen Access

Systems Biology and Multi-Omics Integration: Viewpoints from the Metabolomics Research Community

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Authors

FPFarhana R. PinuPlant & Food Research DBDavid J. BealeQueensland Department of Environment and Science APAmy M. PatenCommonwealth Scientific and Industrial Research Organisation

Discussion

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Implication

Consensus report highlights methods and computational tools for multi-omics integration in systems biology, suggesting downstream metabolites effectively bridge distinct molecular platforms.

Key Points

Identify key analytical methods, software tools, databases, and continuing challenges for integrating multiple omics datasets using principles from metabolomics research.
Synthesized viewpoints, workflows, and expert recommendations generated during a peer consensus session on multi-omics integration at the Australian and New Zealand Metabolomics Conference (ANZMET 2018) in Auckland, New Zealand.
Evaluated computational strategies and biological databases capable of combining metabolomic readouts with genomics, transcriptomics, and proteomics.
Identified downstream metabolites as critical molecular links that reflect interactions across upstream genes, transcripts, and proteins to enable integrated systems-level modeling.
Established strategic recommendations and highlighted ongoing analytical challenges in data harmonization to guide life science researchers conducting multi-omics investigations.

Cite This Study

Pinu et al. (2019) studied this question.

synapsesocial.com/papers/6a0252ab3bcf4d6d91f5ffef https://doi.org/10.3390/metabo9040076

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Implication

Consensus report highlights methods and computational tools for multi-omics integration in systems biology, suggesting downstream metabolites effectively bridge distinct molecular platforms.

Systems Biology and Multi-Omics Integration: Viewpoints from the Metabolomics Research Community

Discussion

Member takes

Implication

Key Points

Cite This Study

Systems Biology and Multi-Omics Integration: Viewpoints from the Metabolomics Research Community

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider