Why the study?
Myocardial calcifications can arise after myocardial damage or calcium and phosphorus balance disturbances and are linked to cardiac sequelae and higher mortality, motivating description of their rapid-onset development in sepsis and renal failure.
Myocardial calcifications can develop rapidly (within 5 to 13 weeks) in patients with sepsis and renal failure on hemodialysis.
May warrant vigilance for rapid myocardial calcification in septic dialysis patients; hypothesis-generating case series requiring prospective confirmation.
Myocardial calcifications can arise following damage to myocardial tissue or in the setting of disturbances in the calcium and phosphorus balance. They are associated with a number of cardiac sequelae, as well as higher mortality. Three cases of rapid-onset myocardial calcifications that developed within the course of 5 to 13 weeks in patients who had a history of sepsis and renal failure while undergoing hemodialysis are described. Baseline imaging from several weeks prior without myocardial calcification are shown for each of the three patients, demonstrating the rapid onset of these calcifications. The clinical significance of these findings is discussed.
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Li et al. (2021) studied this question.
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