Key result
A review of the literature proposes a mechanistic theory for the pathogenesis of myocardial calcification in the context of sepsis.
This review proposes a novel mechanistic theory linking sepsis to the pathogenesis of myocardial calcification.
Raises awareness of myocardial calcification in sepsis; leaves open mechanistic validation in prospective studies.
Myocardial calcification is a rare and life-threatening condition that is a recognised complication of ischaemic heart disease, cardiac surgery, rheumatic fever and myocarditis. It is distinct from coronary artery or valvular calcification, and can be seen in patients with abnormal calcium metabolism1 . Its presence in the context of sepsis is less well recognised and the mechanisms responsible are poorly understood. We review the relevant literature and propose a mechanistic theory for its pathogenesis
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Bower et al. (2017) conducted a review in Myocardial calcification in the context of sepsis. Sepsis was evaluated. A review of the literature proposes a mechanistic theory for the pathogenesis of myocardial calcification in the context of sepsis.
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