Key result
In septic patients with elevated troponin undergoing coronary angiography, acute culprit lesions were identified in only about 10% of patients, indicating most elevations reflect myocardial stress.
Troponin elevation in sepsis primarily reflects myocardial stress rather than acute coronary occlusion, emphasizing that invasive diagnostics should be guided by overall clinical context rather than isolated biomarker values.
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Szczeklik et al. (2025) conducted an editorial in Sepsis with elevated troponin. In septic patients with elevated troponin undergoing coronary angiography, acute culprit lesions were identified in only about 10% of patients, indicating most elevations reflect myocardial stress.
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