In patients with atrial fibrillation, worsening renal function was associated with a marked increase in left atrial thrombus prevalence, rising from 6.7% in patients with CrCl ≥50 ml/min to 19% in those with CrCl <30 ml/min.
Does worsening renal function and inappropriate oral anticoagulant dosing increase the prevalence of left atrial thrombus in patients with atrial fibrillation?
Renal dysfunction and inappropriate direct oral anticoagulant dosing are strongly associated with an increased risk of left atrial thrombus in patients with atrial fibrillation.
Boriani et al. (Fri,) conducted a editorial in Atrial fibrillation (n=2,790). Impaired renal function (CrCl <50 ml/min) vs. Normal or mildly impaired renal function (CrCl ≥50 ml/min) was evaluated on Presence of left atrial thrombus (LAT) detected by transesophageal echocardiography. In patients with atrial fibrillation, worsening renal function was associated with a marked increase in left atrial thrombus prevalence, rising from 6.7% in patients with CrCl ≥50 ml/min to 19% in those with CrCl <30 ml/min.