Key result
Continuous ABPM identifies ambulatory hypertension in ~19% of non-dialyzed adolescents with CKD.
Why the study?
Hypertension is a known complication and modifiable risk factor for CKD, and diurnal variability is better assessed using continuous ambulatory blood pressure monitoring.
Does continuous ambulatory blood pressure monitoring (CABPM) detect hidden hypertension phenotypes compared to casual blood pressure measurement in non-dialyzed children and adolescents with CKD?
Cross-Sectional (n=74)
Does continuous ambulatory blood pressure monitoring (CABPM) detect hidden hypertension phenotypes compared to casual blood pressure measurement in non-dialyzed children and adolescents with CKD?
CABPM reveals a high prevalence of masked hypertension, white coat hypertension, and blunted nocturnal dipping in pediatric CKD patients, highlighting its utility over casual BP measurement.
CABPM may refine hypertension classification in adolescents with CKD; leaves open whether it improves renal outcomes.
Hypertension is a known complication and modifiable risk factor for chronic kidney disease (CKD). Diurnal variability is better assessed using continuous ambulatory blood pressure monitoring (CABPM). We enrolled 74 adolescents (78.4% boys) aged 10-18 years with CKD, excluding those on dialysis or with hypertensive urgency/emergency. Casual blood pressure and CABPM were measured using Omron oscillometric sphygmomanometer and A&D TM2441, respectively. Using CABPM, 12 (16.2%) had white coat hypertension, 7 (9.5%) had masked hypertension, and 14 (18.9%) had ambulatory hypertension. Twenty-eight (37.8%) children had blunted nocturnal dipping and 6.6% had left ventricular hypertrophy (LVH).
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Mahajan et al. (2026) conducted a cross-sectional in Chronic Kidney Disease (n=74). Continuous ambulatory blood pressure monitoring vs. Casual blood pressure was evaluated on Prevalence of hypertension phenotypes and blunted nocturnal dipping. Continuous ambulatory blood pressure monitoring in non-dialyzed adolescents with CKD identified white coat hypertension in 16.2%, masked hypertension in 9.5%, and ambulatory hypertension in 18.9%.
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