Why the study?
Rapid awakening using remimazolam may be beneficial in TAVR by allowing rapid detection of neurologic deficits, but comparative data against conventional sedation regimens were needed.
Does monitored anesthesia care with remimazolam and remifentanil reduce arousal time in patients undergoing transcatheter aortic valve replacement compared to conventional MAC with dexmedetomidine, propofol, and remifentanil?
Population
253 TAVR cases performed under monitored anesthesia care
Comparison
Remimazolam and remifentanil vs dexmedetomidine, propofol, and remifentanil
Design
Single center retrospective propensity score-matched study
Authors
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Shorter arousal with remimazolam-remifentanil MAC may aid rapid TAVR assessment; hypothesis-generating versus dexmedetomidine, needs RCTs before practice change.
Does monitored anesthesia care with remimazolam and remifentanil reduce arousal time in patients undergoing transcatheter aortic valve replacement compared to conventional MAC with dexmedetomidine, propofol, and remifentanil?
Remimazolam combined with remifentanil significantly shortens arousal time compared to dexmedetomidine-based anesthesia during TAVR, facilitating rapid neurologic assessment.
Kitaura et al. (2023) studied this question.
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