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The text discusses the physiological assumption that coronary sinus blood in humans is composed almost entirely of left ventricular efflux, a principle used in measuring coronary blood flow.
Blood samples obtained from the coronary sinus in man contain venous blood draining from left ventricular myocardium. It is believed by many investigators that coronary sinus blood in man is composed almost entirely of left ventricular efflux. That this is true in the canine heart is firmly estab- lished (Rayford et al., 1959). This principle has been widely accepted in the many studies which have been carried out using highly diffusible indi- cators to measure coronary blood flow, in which it is presumed that left ventricular flow per unit muscle mass is being measured (Gorlin, 1960).
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William B. Hood (1968) studied this question.
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