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January 1, 2014Circulation Cardiovascular Quality and OutcomesOpen Access

Risk of Ischemic Stroke After an Acute Myocardial Infarction in Patients With Diabetes Mellitus

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Why the study?

Does the use of evidence-based therapies reduce the risk of ischemic stroke after an acute myocardial infarction in patients with diabetes mellitus?

Population

173,233 unselected patients with an acute myocardial infarction, including 33,503 patients with diabetes…

Comparison

Evidence-based therapies vs Patients without diabetes mellitus; and temporal…

Design

Cohort

Follow-up

1 year

Authors

SJStina JakobssonLBLisa BergströmFBFredrik Björklund

Discussion

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Overview

Stroke incidence after AMI declined over time in diabetes; supports temporal gains but leaves causal roles of therapies open.

Structured PICO

Does the use of evidence-based therapies reduce the risk of ischemic stroke after an acute myocardial infarction in patients with diabetes mellitus?

P
Population
173,233 unselected patients with an acute myocardial infarction (AMI), including 33,503 patients with diabetes mellitus, from the Swedish Register of Information and Knowledge about Swedish Heart Intensive Care Admissions (RIKS-HIA) during 1998 to 2008.
I
Intervention
Evidence-based therapies (reperfusion therapy, acetylsalicylic acid, P2Y12 inhibitors, and statins)
C
Comparator
Patients without diabetes mellitus; and temporal comparison (earlier vs. later years)
O
Outcome
Incidence of ischemic stroke during 1 year of follow-uphard clinical

The risk of ischemic stroke after an acute myocardial infarction in patients with diabetes has significantly decreased over time, largely driven by the increased use of evidence-based therapies including reperfusion, aspirin, P2Y12 inhibitors, and statins.

Cite This Study

Jakobsson et al. (2014) studied this question.

synapsesocial.com/papers/6a026ff819750436f6cb58f2https://doi.org/10.1161/circoutcomes.113.000311
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