Population
Adult population with newly originated episodes of major depression drawn from a general population survey
Design
Cohort
Follow-up
2 years
Authors
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Nearly 20% of MDEs persist ≥24 months; leaves open predictors of chronicity and targeted interventions pending prospective trials.
While half of individuals with a major depressive episode recover within 3 months, nearly 20% experience chronic depression lasting 24 months or more.
Spijker et al. (2002) studied this question.
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