Why the study?
Infections following CIED implantation often result in significant cost, morbidity, and potentially mortality, prompting a systematic review to identify risk factors associated with mortality.
What are the risk factors associated with mortality following CIED infection?
What are the risk factors associated with mortality following CIED infection?
CIED infections carry a high overall mortality of 13.7%, with surgical intervention associated with improved outcomes.
Answers are grounded in this paper and cite their sources.
High mortality after CIED infection warrants early surgical evaluation; meta-analysis reinforces operative benefit in this setting.
BACKGROUND: Infections following cardiac implantable electronic device (CIED) implantation can require surgical device removal and often results in significant cost, morbidity, and potentially mortality. We aimed to systemically review the literature and identify risk factors associated with mortality following CIED infection. METHODS: Electronic searches (up to June 2021) were performed on PubMed and Scopus. Twelve studies (10 retrospective, 2 prospective cohort studies) were included for analysis. Meta-analysis was conducted with the restricted maximum likelihood method, with mortality as the outcome. The overall mortality was 13.7% (438/1398) following CIED infection. CONCLUSION: as the causative organism, and the presence of complications, such as heart failure and embolic phenomena. Surgery, where possible, was associated with better outcomes.
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Ngiam et al. (2022) studied this question.
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