Key result
A multipronged strategy including patient optimization, proper surgical site preparation, prophylactic antibiotics, and antibiotic-impregnated envelopes in high-risk patients is essential to reduce CIED infections.
Why the study?
CIED infections cause significant morbidity, mortality, and healthcare costs, and rising implantation rates and patient comorbidity present ongoing challenges for infection prevention.
A comprehensive review highlighting that patient optimization, proper surgical techniques, prophylactic antibiotics, and antibiotic-impregnated envelopes are key strategies to reduce the risk of CIED infections.
Supports comprehensive CIED infection prevention bundles; leaves open the need for randomized confirmation.
The association between the risk of mortality and cardiovascular implantable electronic device (CIED) infections has been well-established in the literature. As CIED implantations have increased in frequency in the past few decades, the incidence of CIED-related infections has also risen. Given the morbidity, mortality, and health-care costs associated with CIED infections, the prevention of device-related infection is a critical goal. Risk factors for developing CIED infections can be categorized as patient-, procedure-, or device-related. Numerous studies have highlighted different strategies for preventing CIED-related infections, which include patient optimization, device selection, and periprocedural preparation and treatment. Nonetheless, as the comorbidity burden of patients undergoing CIED implantation continues to increase, significant challenges in the successful elimination of CIED-related infections remain. This review provides a comprehensive overview of available evidence-based approaches and strategies to reduce the risk of CIED infections.
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Barbar et al. (2020) conducted a review in Cardiac Implantable Electronic Device (CIED) Infection. Infection prevention strategies (patient optimization, prophylactic antibiotics, antibiotic-impregnated envelopes) was evaluated. A multipronged strategy including patient optimization, proper surgical site preparation, prophylactic antibiotics, and antibiotic-impregnated envelopes in high-risk patients is essential to reduce CIED infections.
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