Does left bundle branch pacing reduce the incidence of new-onset device-detected atrial fibrillation compared to conventional right ventricular pacing in patients older than 70 years requiring pacemaker implantation?
In older patients requiring pacemaker implantation, left bundle branch pacing is associated with a significantly lower risk of new-onset device-detected atrial fibrillation compared to conventional right ventricular pacing.
Background: Right ventricular pacing (RVP) has been associated with an increased risk of atrial fibrillation (AF). Objective: We aim to compare the incidence of new-onset AF between left bundle branch pacing (LBBP) and RVP. Methods: We conducted a prospective, observational, 2-center study recruiting patients with pacemaker implantation who were at high risk of developing AF (ie, patients older than 70 years). The primary end point was time to the first occurrence of device-detected AF with clinical significance (ie, AF lasting >6 minutes), whereas the secondary end point was time to the first episode of AF that could require oral anticoagulation (ie, AF lasting >24 hours). Multivariate Cox regression models were used to evaluate the effect of LBBP on AF occurrence. Results: 6 minutes and decreased the likelihood of new-onset AF episodes lasting >24 hours, compared with RVP in a high-risk population for AF development.
Ramos‐Maqueda et al. (Fri,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: