May 1, 1994Pacing and Clinical Electrophysiology
Short‐and Long‐Term Reproducibility of QT, QTc, and QT Dispersion Measurement in Healthy Subjects
Why the study?
What is the interobserver and intrasubject reproducibility of QT interval duration and dispersion measurements in healthy subjects?
Population
28 healthy volunteers
Design
Cohort, Two independent observers analyzed each ECG record
Follow-up
30 days
Authors
Discussion
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Member takes
Implication
QT dispersion's nonreproducibility warrants clinical caution; leaves open standardized alternatives and validation in disease cohorts.
Structured PICO
What is the interobserver and intrasubject reproducibility of QT interval duration and dispersion measurements in healthy subjects?
P
Population
28 healthy volunteers
I
Intervention
Standard 12-lead ECGs recorded at 25 mm/sec, performed 1, 7, and 30 days apart and analyzed by two independent observers
O
Outcome
Interobserver and intrasubject (short-term and long-term) reproducibility of QT interval duration and dispersionsurrogate
While QT interval duration is a stable and reproducible metric on standard ECGs, QT dispersion is highly nonreproducible, questioning its clinical reliability.
Cite This Study
Kautzner et al. (1994) studied this question.