Why the study?
Treatment of severe inpatient hypertension developing during hospitalization is not guideline-informed, and intravenous antihypertensives used without acute target organ damage may cause unpredictable blood pressure reduction and cardiovascular events.
Do intravenous antihypertensives increase the risk of adverse clinical outcomes in hospitalized adults with severe hypertension without acute target organ damage?
Do intravenous antihypertensives increase the risk of adverse clinical outcomes in hospitalized adults with severe hypertension without acute target organ damage?
The use of intravenous antihypertensives for severe inpatient hypertension without acute target organ damage is associated with an increased risk of myocardial injury, suggesting they should be used with caution.
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IV antihypertensives were associated with myocardial injury in severe hypertension; hypothesis-generating and requires randomized confirmation.
Ghazi et al. (2022) studied this question.
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