Demonstrates enhanced antitumor immunity in tumors using engineered bacteria and dendritic cells, implying a novel treatment approach.
T cell infiltration, and suppresses tumor growth and metastatic burden. The system also prolongs survival and remains controllable by antibiotic-mediated clearance. These findings support a programmable microbial-cellular strategy for localized cytokine delivery and immune activation in immunologically cold tumors.
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Deng et al. (2026) studied this question.
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