Glioblastoma is the most common and aggressive primary brain tumor in adults. However, despite its aggressive nature, dural-based progression remains exceedingly rare. This rarity is partially due to the protective effects of the blood-brain barrier and the poor survival of affected patients. As a result, the pathophysiology and imaging characteristics of dural-based glioblastoma progression remain poorly understood and underreported. In this case series, we present 4 cases of glioblastoma with dural-based progression and review the relevant literature. We highlight the MRI imaging features of dural progression and explore potential pathophysiology, diagnosis, and management in this rare manifestation.
Wang et al. (Sat,) studied this question.