What question did this study set out to answer?

This review aims to synthesize evidence on the use of AI in interpreting prostate MRI scans in asymptomatic men for cancer screening.

May 12, 2026European Journal of Radiology0 citationsOpen Access

Use of Artificial Intelligence in prostate MRI: A rapid scoping review highlighting limited evidence in screening context

DSDeependra Singh JGJuan Pablo Salazar Gutiérrez OROlivier Rouvière

Puntos clave

This review aims to synthesize evidence on the use of AI in interpreting prostate MRI scans in asymptomatic men for cancer screening.
Conducted a rapid scoping review following PRISMA-ScR guidelines and Cochrane methods.
Performed systematic searches of major databases and grey literature with no restrictions on study design.
Assessed 284 records, with 47 studies evaluated for eligibility; only two studies met inclusion criteria.
AI algorithm showed poor to moderate agreement with expert radiologists (kappa 0.17-0.42).
High tendency for over-detection and low specificity led to discordance with experts.
Current evidence is limited, indicating that more robust training and testing of AI in real screening populations are required.

Resumen

Background and Objective: Artificial Intelligence (AI) is seen as a potential solution to alleviate workforce demands arising from growing use of magnetic resonance imaging (MRI) in prostate cancer (PCa) screening.We aimed to synthesize the evidence on use of AI in prostate MRI readings in asymptomatic men in PCa screening settings. Methods:We conducted a rapid scoping review following PRISMA-ScR guidelines and Cochrane rapid review methods performing the systematic search of major databases supplemented by grey literature search with no restrictions in study design and time-duration.We considered various aspects of utilization of AI in MRI interpretations and biopsy indications in the screening setting.Anticipating limited evidence on AI implementation in screening settings, we extended the review from 'what is known' to discussion on 'key considerations for expected expansion'. Key findings and limitations:We identified 284 records with 47 studies assessed for eligibility and two studied met the inclusion criteria.Both evaluated commercially available ProstateAI software tool to interpret prostate MRI.Agreement between deep learning-based algorithm of AI and expert radiologist ranged from poor to moderate (kappa 0.17-0.42).AI demonstrated high tendency of over-detection and low specificity, leading to discordance with expert radiologists. Conclusions and clinical implications:Current evidence on use of AI in prostate MRI interpretation is limited, but this review highlights several important directions for future research and implementation.Generating robust evidence base in the coming years will be crucial to ensure that AI integration enhances the effectiveness and acceptability of future prostate cancer screening programs. Patient summary:In this study, we examined whether artificial intelligence (AI) tools can accurately read prostate MRI scans of apparently healthy men for early detection of prostate cancer.We found that deploying current AI tools that are trained and tested in hospital referred patients may not be optimal to read MRI performed in asymptomatic men.We conclude that AI needs much more training and testing in real screening populations before it can be safely used in prostate cancer screening programs.

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