Key result
Elevated Neutrophil Percentage-To-Albumin Ratio (NPAR) demonstrated modest discriminative ability for predicting all-cause mortality in patients with chronic kidney disease (AUC = 0.601, p<0.001).
Why the study?
Does an elevated Neutrophil Percentage-To-Albumin Ratio (NPAR) predict all-cause and cardiovascular mortality in patients with chronic kidney disease?
Observational
Does an elevated Neutrophil Percentage-To-Albumin Ratio (NPAR) predict all-cause and cardiovascular mortality in patients with chronic kidney disease?
Effect estimate: AUC 0.601
p-value: p=<0.001
Elevated NPAR is associated with a higher likelihood of cardiovascular and all-cause mortality in patients with CKD, suggesting its potential as a prognostic biomarker.
value <0.001. ROC analysis showed that NPAR had modest discriminative ability for predicting all-cause mortality (AUC = 0.601), with an optimal cutoff value of 1.48. Across different subgroups, NPAR reliably predicted CVD and all-cause mortality in CKD patients.ConclusionElevated NPAR were linked with a higher likelihood of CVD mortality and all-cause mortality in patients with CKD and could serve as an effective prognostic biomarker.
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Wu et al. (2026) conducted an observational in Chronic Kidney Disease. Neutrophil Percentage-To-Albumin Ratio (NPAR) was evaluated on All-cause mortality (AUC 0.601, p=<0.001). Elevated Neutrophil Percentage-To-Albumin Ratio (NPAR) demonstrated modest discriminative ability for predicting all-cause mortality in patients with chronic kidney disease (AUC = 0.601, p<0.001).
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