Why the study?
Does activation of adenosine A2A and A2B receptors contribute to ischemic coronary dilation via KV and KATP channels in dogs?
Does activation of adenosine A2A and A2B receptors contribute to ischemic coronary dilation via KV and KATP channels in dogs?
Adenosine A2A receptors mediate coronary vasodilation in response to cardiac ischemia through the activation of KV and KATP channels.
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A2A inhibition attenuates ischemic coronary hyperemia via KV/KATP in dogs; leaves open translation to human microvascular therapeutics.
Berwick et al. (2010) studied this question.
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