What question did this study set out to answer?

To provide evidence-based recommendations for the prevention, diagnosis, and clinical management of infectious complications in patients with inflammatory bowel disease receiving immunosuppressive therapies.

March 13, 2021Journal of Crohn s and ColitisOpen Access

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

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To provide evidence-based recommendations for the prevention, diagnosis, and clinical management of infectious complications in patients with inflammatory bowel disease receiving immunosuppressive therapies.
Convened an international panel of experts under the European Crohn's and Colitis Organisation (ECCO) to evaluate current literature on infection risks in inflammatory bowel disease.
Reviewed safety evidence concerning conventional immunomodulators, biologic agents, and small-molecule Janus kinase (JAK) inhibitors.
Outlines standardized pre-treatment screening and immunization protocols to reduce the incidence of preventable opportunistic infections.
Provides clinical algorithms for diagnostic workups and therapeutic interventions when viral, bacterial, parasitic, or fungal infections occur during IBD therapy.

Implication

Clinical practice guideline reveals strategies for preventing and managing opportunistic infections in inflammatory bowel disease, highlighting safety protocols for advanced therapies.

Abstract

INTRODUCTION : The introduction and broad use of new immunosuppressive agents, including biologic agents and JAK inhibitors, have revolutionised treatment of inflammatory bowel disease [IBD] in recent decades. With such immunosuppression, the potential for opportunistic infection is a key safety concern. [...]

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Cite This Study

Kucharzik et al. (2021) studied this question.

synapsesocial.com/papers/6a0330f61abe013fb89e3e11 https://doi.org/10.1093/ecco-jcc/jjab052

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Implication

Clinical practice guideline reveals strategies for preventing and managing opportunistic infections in inflammatory bowel disease, highlighting safety protocols for advanced therapies.

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

Key Points

Implication

Abstract

Discussion

Cite This Study

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

Key Points

Implication

Abstract

Discussion

Cite This Study

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