The Clinical and Imaging Characteristics Associated With Neurological Sequelae of Pediatric Patients With Acute Necrotizing Encephalopathy

Figures

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  Figure 1. The difference of (A) ANE-SS and (B) MRI scoring system in 34 survival ANE patients with varying degrees of neurological sequelae. The one-way ANOVA (ANE-SS) and Kruskal–Wallis test (MRI scoring system) method were used to determine the differences among groups.

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  Figure 2. The association of lesions in brain to the severity of neurological sequelae in ANE patients. (A) Distribution difference in the number of brain lesion locations in 34 survival ANE patients with varying degrees of neurological sequelae. (B) The association of brain lesion locations to the severity of neurological sequelae in 34 survival ANE patients.

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  Figure 3. The association of neuroimaging evolution and neurological sequelae of ANE. The dynamic changes in (A,B) brain hemorrhage, (C,D) cavitation, and (E,F) atrophy in 34 survival ANE patients with different degrees of neurological sequelae during the follow-up.

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  Figure 4. Representative dynamic MRI images of survival ANE patients with different degrees of neurological sequelae. Case 1 with severe, case 2 with moderate and case 3 with mild neurological sequelae. Arrow in red indicates hemorrhage and white indicates cavitation.