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Cross-sectional study reveals vaginal microbiota shifts toward dysbiotic community types with HPV infection and advancing age, highlighting microbial markers of viral progression.
With the development of disease, the proportions of community state type III (CST-III) and CST-IV-B gradually increased, whereas the proportions of CST-I and CST-IV-A gradually decreased. In addition, age was an influential factor for HPV infection. With aging, the probability of HPV infection and the proportion of CST-IV-B increase. In conclusion, our study was a large cross-sectional study that evaluated the relationship between vaginal microbiota and HPV infection, and brought essential comparable data.
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Zhang et al. (2022) studied this question.
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