The size of it: Mesoporous silica nanoparticles (MSNs) of controlled size in the range 30 to 280 nm are obtained by adjusting the pH of the reaction solution. The uptake of fluorescein-labeled MSNs (green, see image) by HeLa cells is size-dependent, with maximum uptake at a nanoparticle size of 50 nm.
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Lu et al. (2009) studied this question.
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