Laboratory abnormalities in patients with COVID-2019 infection
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Discussion
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Implication
Systematic review reveals elevated procalcitonin and high coagulopathy rates in severe COVID-19, highlighting the necessity of routine hemostatic monitoring.
Key Points
- To provide an overview of the most frequent laboratory abnormalities and prognostic biomarkers in patients with COVID-19.
- Electronic database search conducted in Medline (PubMed), Scopus, and Web of Science without date or language restrictions using keywords for novel coronavirus.
- Identified studies describing significant laboratory abnormalities in severe COVID-19 were analyzed, along with crosschecked references.
- Serum procalcitonin is typically normal at hospital admission, but progressive increases mirror bacterial superinfection and indicate a deteriorating clinical prognosis.
- Laboratory criteria for disseminated intravascular coagulation (DIC) are present in nearly three-fourths (~75%) of patients who died from COVID-19.
Cite This Study
Lippi et al. (2020) studied this question.