Why the study?
Does intracoronary injection of autologous mononuclear bone marrow cells improve left ventricular function in patients with acute anterior STEMI treated with PCI?
Population
100 patients with acute ST-elevation myocardial infarction of the anterior wall treated with percutaneous…
Comparison
Intracoronary injection of autologous… vs Control group
Design
RCT, Randomly assigned, Not blinded
Follow-up
6 months
Authors
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No support for intracoronary BMC after anterior STEMI; challenges earlier positive reports and does not warrant clinical adoption.
Does intracoronary injection of autologous mononuclear bone marrow cells improve left ventricular function in patients with acute anterior STEMI treated with PCI?
Intracoronary injection of autologous mononuclear bone marrow cells following acute anterior STEMI does not significantly improve global left ventricular function at 6 months.
Lunde et al. (2006) studied this question.
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