Why the study?
Does left atrial structure and function differ between patients with HFrEF and HFpEF?
Does left atrial structure and function differ between patients with HFrEF and HFpEF?
Left atrial myopathy is not specifically related to HFpEF, as patients with HFrEF demonstrate worse LA global function despite a lower burden of atrial fibrillation.
LA dysfunction is greater in HFrEF than HFpEF; challenges the view that left atrial myopathy is specific to HFpEF.
[WMD = 16.3% (22.05,8.61); p < 0.001], and higher E/e' [WMD = -0.40 (-0.56, -0.24); p < 0.05], while LAVi was comparable. When focusing on acute hospitalized patients, E/e' was comparable between patients with HFrEF and HFpEF. Despite the higher burden of AF in HFpEF, patients with HFrEF had worse LA global function. Left atrial myopathy is not specifically related to HFpEF.
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Jin et al. (2022) studied this question.
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