Structural determination of natural products at speeds and scale of high-throughput screening

Christopher C. Thornburg; Rohitesh Kumar; D J Wang; Barry R. O’Keefe; Tanja Grkovic

doi:10.1039/d6np00016a

January 1, 2026Natural Product ReportsOpen Access

Structural determination of natural products at speeds and scale of high-throughput screening

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Key Points

This review focuses on the analytical techniques for determining the structures of natural products.
Review of various analytical techniques used in structural elucidation.
Discussion on high-throughput screening campaigns for natural products.
Highlights advancements in structural determination methodologies.
Shows the efficiency of high-throughput screening in natural product analysis.

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Implication

This review demonstrates structural determination of natural products using analytical techniques in high-throughput screening, suggesting improved efficiencies.

Abstract

This review highlights analytical techniques and methods used for the structural elucidation of natural products in high-throughput screening campaigns.

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Thornburg et al. (2026) studied this question.

synapsesocial.com/papers/6a03cbe01c527af8f1ecfa76 https://doi.org/10.1039/d6np00016a

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Structural determination of natural products at speeds and scale of high-throughput screening

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Structural determination of natural products at speeds and scale of high-throughput screening

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