Comparison
Direct oral anticoagulants vs vitamin K antagonists (warfarin)
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Requires vigilant DOAC selection and monitoring in frailty, obesity, and CKD; leaves open optimal strategies in contraindicated populations.
DOACs are the standard of care for many anticoagulation indications but require careful patient selection and monitoring in specific high-risk, frail, or complex populations.
Olie et al. (2023) studied this question.
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