Lymantria dispar L. larvae treated with either 5.0 or 1.0 ppm abamectin or 100 or 50 ppm Milbemycin D had significantly reduced frass output and weight gain, indicating feeding cessation. All sublethal concentrations delayed molting by at least 1 d. Larvae treated with 10, 5.0, or 1.0 ppm of Milbemycin D had increased frass output and weight gain compared with controls; they also exhibited wandering. Avermectin at all concentrations and milbemycin at higher sublethal concentrations appeared to act as depressants. At lower concentrations, milbemycin acted as a stimulant. Larvae treated with avermectin had a 12% occurrence of atypical morphological development compared with a 2% occurrence for larvae treated with milbemycin. Larvae treated with sublethal concentrations of carbaryl showed different physiological responses when compared with responses to either avermectin or milbemycin.
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Deecher et al. (1990) studied this question.