Why the study?
What are the clinical, laboratory, and echocardiographic characteristics that distinguish Kawasaki disease shock syndrome from hemodynamically normal Kawasaki disease?
Population
187 consecutive patients with Kawasaki disease treated at a single institution during a 4-year period.
Comparison
Kawasaki disease shock syndrome, defined by… vs Hemodynamically normal Kawasaki disease.
Design
Cohort
Follow-up
Acute and convalescent phases
Authors
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Supports closer monitoring for cardiac complications in KDSS; leaves open whether intensified therapy improves outcomes.
What are the clinical, laboratory, and echocardiographic characteristics that distinguish Kawasaki disease shock syndrome from hemodynamically normal Kawasaki disease?
Kawasaki disease shock syndrome is a severe phenotype associated with greater inflammation, myocardial dysfunction, coronary artery abnormalities, and resistance to standard immunoglobulin therapy.
Kanegaye et al. (2009) studied this question.
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