Why the study?
What are the clinical, laboratory, and echocardiographic characteristics that distinguish Kawasaki disease shock syndrome from hemodynamically normal Kawasaki disease?
What are the clinical, laboratory, and echocardiographic characteristics that distinguish Kawasaki disease shock syndrome from hemodynamically normal Kawasaki disease?
Kawasaki disease shock syndrome is a severe phenotype associated with greater inflammation, myocardial dysfunction, coronary artery abnormalities, and resistance to standard immunoglobulin therapy.
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Supports closer monitoring for cardiac complications in KDSS; leaves open whether intensified therapy improves outcomes.
Kanegaye et al. (2009) studied this question.
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