Intelligent Visualization Frameworks Driven by AI for Multi-Dimensional Genomic Data Exploration and Interpretation

In the era of high‑throughput sequencing and multi‑omics profiling, the volume and complexity of genomic data pose significant challenges for researchers seeking to generate actionable insights. Traditional static visualization tools often fail to accommodate the scale, heterogeneity, and dimensionality of modern genomic datasets. Artificial intelligence (AI) offers transformative potential for advanced visualization: interactive, adaptive, and insight‑driven tools that support exploration, pattern detection and hypothesis generation. This paper presents a comprehensive framework for developing AI‑powered visualization systems tailored to genomic data workflows. We describe key components including data ingestion, feature embedding, dimensionality reduction, graph‑neural network based layout generation, and interactive UI modules. A prototype application was evaluated on three use‑cases: whole‑genome variant distributions (n = 2,000 samples), transcriptome‑variant integration (n = 500), and 3D chromatin interaction visualization (Hi‑C data, n = 50). The AI‑augmented visualizations enabled users to identify sub‑population clusters 30 % faster than baseline tools, and to detect rare variant hotspots previously overlooked in manual reviews. We discuss challenges such as model interpretability, user‑interface design, real‑time interaction at scale, and dataset bias. Finally, we outline future directions including self‑supervised visualization embedding, immersive VR/AR genomics dashboards, federated collaborative visualization and deployment in clinical genomics settings. In conclusion, AI‑powered visualization tools hold the promise to democratize access to complex genomic data, accelerate discovery and enhance the interpretability of large‑scale genomics studies—provided that rigorous design, user‑centred workflows and open standards are embraced.