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Investigates anti-inflammatory activity of gold nanoparticles in LPS-induced RAW 264.7 cell lines, suggesting potential for new treatments.
value of 9.7 ± 1.38 µg/mL. RT-PCR analysis revealed that SM-Au NPs IC50 at 9.7 µg/mL significantly down-regulates the expression of pro-inflammatory cytokines to IL-1β 0.2 (**p ≤ 0.01), TNF-α to 0.51 (**p ≤ 0.01), and up-regulates anti-inflammatory cytokine TGF-β to 83.59-fold (**p ≤ 0.01) folds at in comparison with SM-AQ and LPS controls. Our study revealed that SM-Au NPs emphasized their potential use to develop new anti-inflammatory agents by using Solanum marginatum.
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Gebreyesus et al. (2026) studied this question.
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