Biosynthesized gold nanoparticles exhibit potential antimicrobial, antioxidant, anticancer, and antiviral effects, indicating promising therapeutic applications.
The current study of the biosynthesized Sm-AuNPs reveals a SPR peak at 554 nm indicating reduction of gold chloride to gold nanoparticles (Sm-AuNPs). Fourier Infrared Spectroscopy revealed that different bioactive compounds of bark extract were involved in reduction and stabilization of Sm-AuNPs. Transmission Electron Microscopy and EDX analysis of Sm-AuNPs reveals that the nanoparticles spherical in shape. The Sm-AuNPs are poly-dispersed in nature, with a poly-disperse index about 0.310 and high negative zeta potential value of -62.5 mV. The Sm-AuNPs reveals excellent antioxidant, antibacterial, anticancer activities and anti-viral properties. The results revealed that the Sm-AuNPs have an excellent antibacterial activity when compared with standard antibiotics while they also reveal a significant antioxidant activity. The anticancer studies on SKOV ovarian cancer cell line by Sm-AuNPs was carried by MTT assay, reveals that IC50 value was 64.19 µg/ml and the apoptotic cells were detected by Dual fluorescence assay. Apart from the above studies, the antiviral efficacy of Sm-AuNPs on New Castle Disease (NDV) was carried out in embryonated chicken eggs, reveals that the Sm-AuNPs have very good and considerable antiviral properties. The green synthesized Sm-AuNPs can useful as future therapeutic agents to control cancer and NDV effectively.
No takes yet. Share an insight, caveat, or question.
Kotakadi et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: