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May 13, 2026AnimalsOpen Access

An Assessment of Anti-Ganglioside Antibodies for the Diagnosis of Avian Ganglioneuritis and Potential Correlation with Gross Lesions, Microscopic Findings and Serologic Titers in Cockatiels Challenged with Parrot Bornavirus

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Authors

BBBianca BückingAGAnna Maria GartnerSHS. Herzog

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Overview

Randomized trial assesses anti-ganglioside antibodies' role in avian ganglioneuritis diagnosis, indicating no significant association.

Key Points

  • To evaluate anti-ganglioside antibodies as diagnostic markers for avian ganglioneuritis in cockatiels.
  • 257 plasma samples from cockatiels experimentally infected with parrot bornavirus were tested for anti-ganglioside antibodies.
  • Results were compared with clinical signs, gross pathological findings, and histopathological results.
  • Blinded testing was performed by a commercial laboratory.
  • 9 out of 25 birds with dilated proventriculi tested positive for anti-ganglioside antibodies (36%).
  • 26 out of 56 birds with histopathological avian ganglioneuritis tested positive (46.43%).
  • No significant association between anti-ganglioside antibody detection and avian ganglioneuritis was found.

Cite This Study

Bücking et al. (2026) studied this question.

synapsesocial.com/papers/6a04153d79e20c90b4445115https://doi.org/10.3390/ani16101466
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Also Consider

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  1. 1Detection of Herpesviruses in Cockatoos (Cacatuidae) in Europe2025
  2. 2PARROT BORNAVIRUSES IN PSITTACINES KEPT IN CAPTIVITY IN THE STATE OF SANTA CATARINA, BRAZIL2024
  3. 3A pegivirus associated with encephalitis in red-legged partridges shows neurotropism across avian species2026
  4. 4Molecular epidemiology of parrot bornaviruses in Guangdong, China: co-circulation of three genotypes in captive parrots2026
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