Answers are grounded in this paper and cite their sources.
Proteinase activated receptor-2 plays a crucial role in a wide variety of conditions with a strong inflammatory component. We present the discovery and characterization of two structurally different, potent, selective, and metabolically stable small-molecule PAR-2 agonists. These ligands may be useful as pharmacological tools for elucidating the complex physiological role of the PAR-2 receptors as well as for the development of PAR-2 antagonists.
No takes yet. Share an insight, caveat, or question.
Seitzberg et al. (2008) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: