Key result
Elevated perioperative BNP strongly predicts MACE and mortality in high-risk noncardiac surgery.
Why the study?
Does measurement of BNP or NT-proBNP improve prediction of perioperative major adverse cardiovascular events and mortality in high-cardiovascular risk patients undergoing noncardiac surgery?
Does measurement of BNP or NT-proBNP improve prediction of perioperative major adverse cardiovascular events and mortality in high-cardiovascular risk patients undergoing noncardiac surgery?
The addition of BNP or NT-proBNP to perioperative risk calculators significantly improves the prediction of MACE and mortality in high-risk patients undergoing noncardiac surgery.
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May enhance risk stratification in high-risk noncardiac surgery; leaves open effects on clinical outcomes.
Malhotra et al. (2016) conducted a review in High cardiovascular-risk patients undergoing noncardiac surgery. Brain natriuretic peptide (BNP) and NT-proBNP measurement vs. Standard clinical risk stratification was evaluated on Major adverse cardiovascular events (MACE) and mortality. Elevated perioperative brain natriuretic peptide levels strongly predict major adverse cardiovascular events and mortality in high-risk patients undergoing noncardiac surgery.
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