Key result
Current smoking linked to ~3-fold greater risk of sudden cardiac death vs never smoking.
Why the study?
Does tobacco smoking increase the risk of sudden cardiac death?
Meta-Analysis
Does tobacco smoking increase the risk of sudden cardiac death?
This meta-analysis confirms a strong, dose-dependent association between tobacco smoking and an increased risk of sudden cardiac death, which is partially mitigated but not eliminated by smoking cessation.
May prioritize smoking cessation in SCD prevention; confirms association across prospective cohorts.
= 0.30). The results persisted in most of the subgroup analyses. There was no evidence of publication bias. These results confirm that smoking increases the risk of sudden cardiac death. Any further studies should investigate in more detail the effects of duration of smoking, number of cigarettes per day, pack-years, and time since quitting smoking and sudden cardiac death.
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Aune et al. (2018) conducted a meta-analysis in Sudden cardiac death. Current smoking vs. Never smokers was evaluated on Sudden cardiac death (RR 3.06, 95% CI 2.46-3.82). Current smoking was associated with a threefold increase in the risk of sudden cardiac death (RR 3.06) compared to never smoking.
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