Key result
Higher mean beat frequency during ventricular fibrillation in a postinfarct ovine model was strongly associated with lower cycle duration variability (r=-0.91, P<0.001), often at intramural sites.
Effect estimate: r=-0.91
p-value: p=<0.001
In a chronic postinfarct ovine model, regions with the highest frequency of activation during VF were usually intramural and associated with low local cycle duration variability, supporting the presence of stable periodic sources.
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Should not inform clinical VF management; leaves open whether stable intramural sources drive postinfarct VF in humans.
Thomas et al. (2005) studied Ventricular fibrillation after myocardial infarction (n=12). Electrical activation recording with multielectrode transmural plunge needles during induced VF was evaluated on Association between mean beat frequency and SD of cycle duration intervals (r=-0.91, p=<0.001). Higher mean beat frequency during ventricular fibrillation in a postinfarct ovine model was strongly associated with lower cycle duration variability (r=-0.91, P<0.001), often at intramural sites.
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