Key result
Exercise tolerance testing demonstrated a positive predictive value of 77% for diagnosing coronary artery disease in diabetic patients presenting with atypical chest discomfort.
Why the study?
Does Exercise Tolerance Testing accurately diagnose Coronary Artery Disease in diabetic patients with atypical chest discomfort?
Cross-Sectional (n=130)
No
Does Exercise Tolerance Testing accurately diagnose Coronary Artery Disease in diabetic patients with atypical chest discomfort?
Exercise Tolerance Testing has a 77% positive predictive value for diagnosing CAD in diabetic patients with atypical chest discomfort, supporting its use as a non-invasive screening tool.
May support ETT screening in diabetics with atypical symptoms; leaves open need for prospective validation.
BACKGROUND: Coronary artery disease is the single most important cause of mortality and morbidity in diabetic patients. Electrocardiographic stress test is a non-invasive modality to screen significant coronary involvement in minimally symptomatic diabetics. OBJECTIVES: We investigated the Positive Predictive Value (PPV) of this test in comparison with coronary angiography. MATERIALS AND METHODS: 130 diabetic patients with atypical chest discomfort were studied and tested using Exercise Tolerance Test (ETT) among which 100 cases showed positive results that further were studied invasively by selective coronary angiography. RESULTS: The positive predictive value of ETT for diagnosis of Coronary Artery Disease (CAD)among diabetic patients presented with atypical chest discomfort was 77%. CONCLUSION: We conclude that electrocardiographic stress test is a valuable inexpensive non-invasive screening test in diabetic patients with atypical chest discomfort.
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Gheydari et al. (2012) conducted a cross-sectional in Diabetes mellitus with atypical chest discomfort (n=130). Exercise Tolerance Test (ETT) vs. Coronary angiography was evaluated on Positive predictive value (PPV) for diagnosis of Coronary Artery Disease (CAD). Exercise tolerance testing demonstrated a positive predictive value of 77% for diagnosing coronary artery disease in diabetic patients presenting with atypical chest discomfort.
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