Key result
The Exercise Tolerance Test demonstrated a 76% sensitivity and 87% specificity for detecting latent coronary artery disease in asymptomatic men with risk factors.
Why the study?
Does the Exercise Tolerance Test accurately detect latent coronary artery disease in asymptomatic men with risk factors?
Observational (n=100)
No
Does the Exercise Tolerance Test accurately detect latent coronary artery disease in asymptomatic men with risk factors?
The Exercise Tolerance Test is a reliable screening tool with 76% sensitivity and 87% specificity for detecting latent coronary artery disease in asymptomatic men with multiple risk factors.
May support ETT screening for latent CAD in asymptomatic high-risk men; leaves open prospective validation before practice change.
Objective: To ascertain the role of Exercise Tolerance Test as ascreening tool for coronary artery disease, in asymptomatic men who had one or more risk factors for developingischemic heart disease. Design: A descriptive study. Place and Time Period: Department of Medicine PAF HospitalMushaf Sarghoda from March 2004 to March 2005. Patients and Methods: A total no of 100 asymptomatic men age25-50 years with mean age of 38 years were included in the study. They were divided in to five groups according tonumber of risk factors they had for developing CAD. Following risk factors were included in the study (hypertension,diabetes ,smoking, obesity, hyper-lipidemia, family history of CAD.). All of them underwent E.T.T over treadmill usingmodified Bruce protocol. Test was considered positive if 2mm or more ST segment depression was noted .those testedpositive had coronary angiogram done to confirmed IHD. Results: Seven out of 100 tested positive for IHD on E.T.T.Those tested positive underwent coronary angiography 6 out of seven showed significant narrowing of coronaryarteries and 1 had normal angiogram. These results showed that E.T.T has a 76% sensitivity and 87% Specificity.Conclusion: E.T.T is an important, reliable and cost effective test to detect latent CAD in asymptomatic persons whohad multiple risk factors for developing CAD.
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Ahmad et al. (2006) conducted an observational in Latent Coronary Artery Disease (n=100). Exercise Tolerance Test vs. Coronary angiography was evaluated on Diagnostic accuracy (sensitivity and specificity) for detecting latent CAD. The Exercise Tolerance Test demonstrated a 76% sensitivity and 87% specificity for detecting latent coronary artery disease in asymptomatic men with risk factors.
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