Key result
TAVR linked to ~62% less patient-prosthesis mismatch but higher paravalvular leak versus SAVR.
Why the study?
The study compared clinical outcomes between transcatheter and surgical aortic valve replacements, focusing specifically on postoperative valvular performance assessed by echocardiography.
Does transcatheter aortic valve replacement improve postoperative valvular performance and clinical outcomes compared to surgical aortic valve replacement in patients with severe aortic stenosis?
Cohort (n=425)
Does transcatheter aortic valve replacement improve postoperative valvular performance and clinical outcomes compared to surgical aortic valve replacement in patients with severe aortic stenosis?
Answers are grounded in this paper and cite their sources.
TAVR provides superior effective orifice area and less patient-prosthesis mismatch compared to SAVR, but is associated with higher rates of paravalvular leak, resulting in similar overall clinical outcomes.
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Saito et al. (2022) conducted a cohort in Severe Aortic Stenosis (n=425). Transcatheter aortic valve replacement (TAVR) vs. Surgical aortic valve replacement (SAVR) was evaluated on Patient-prosthesis mismatch (PPM) (p=< 0.001).
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