Key result
SCAD increasingly causes non-atherosclerotic ACS and requires careful distinction from atherosclerotic and iatrogenic dissections.
Spontaneous coronary artery dissection (SCAD) is an important cause of non-atherosclerotic acute coronary syndromes that must be distinguished from atherosclerotic and iatrogenic dissections.
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Supports SCAD consideration in non-atherosclerotic ACS; leaves open standardized diagnostic and management strategies.
Spontaneous coronary artery dissection (SCAD) is an increasingly recognised cause of non-atherosclerotic acute coronary syndromes leading to myocardial infarction. It is characterised by the presence of blood entering and separating the layers of the coronary arterial wall to form a false lumen. This leads to external compression of the true coronary lumen restricting coronary blood flow and leading to coronary insufficiency (Figure 1). SCAD should be distinguished from atherosclerotic dissections arising from plaque rupture events or erosions allowing blood to enter the intimal space and from iatrogenic dissections arising during coronary procedures.
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Al-Hussaini et al. (2017) conducted a review in Spontaneous coronary artery dissection. Spontaneous coronary artery dissection is an increasingly recognised cause of non-atherosclerotic acute coronary syndromes that must be distinguished from atherosclerotic and iatrogenic dissections.
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