Key result
Left bundle branch area pacing with cardiac resynchronization therapy-defibrillator increased left ventricular ejection fraction from 32% to 47% at 6 months in a patient with LBBB-induced cardiomyopathy.
Why the study?
Current guidelines do not provide specific recommendations for left bundle branch area pacing in cardiac resynchronization therapy, underscoring the need for additional evidence regarding its safety and efficacy.
Does LBBAP-CRTD improve cardiac synchronization parameters in a patient with LBBB-induced cardiomyopathy?
Case Report (n=1)
No
Does LBBAP-CRTD improve cardiac synchronization parameters in a patient with LBBB-induced cardiomyopathy?
Answers are grounded in this paper and cite their sources.
This case report suggests that LBBAP-CRTD can increase conduction velocity and improve cardiac synchronization in LBBB-induced cardiomyopathy.
Several studies have suggested that the application of left bundle branch area pacing (LBBAP) in cardiac resynchronization therapy (CRT) holds promise as a treatment modality for correcting left bundle branch block (LBBB) while concurrently enhancing left ventricular structure and function. However, it's noteworthy that current guidelines do not provide specific recommendations for the use of left bundle branch area pacing, underscoring the need for additional evidence regarding its safety and efficacy. In this context, we present a case report detailing the utilization of LBBAP-CRTD treatment in a patient with LBBB-induced cardiomyopathy. The investigation encompasses a thorough examination of the efficacy and safety of LBBAP-CRTD, with a particular emphasis on cardiac synchronization parameters. Written consent was obtained from the patient, and this case report adheres to the CARE guideline.
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Zhang et al. (2025) conducted a case report in LBBB-induced cardiomyopathy and heart failure (n=1). Left bundle branch area pacing (LBBAP) with CRT-D vs. Baseline was evaluated on Left ventricular ejection fraction (LVEF). Left bundle branch area pacing with cardiac resynchronization therapy-defibrillator increased left ventricular ejection fraction from 32% to 47% at 6 months in a patient with LBBB-induced cardiomyopathy.
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