Lipoxygenases: Occurrence, Functions, Catalysis, and Acquisition of Substrate

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Lipoxygenases are a diverse family of enzymes present in plants, fungi, and animals that catalyze the oxygenation of polyunsaturated fatty acids to either initiate specific signaling pathways or induce structural and metabolic changes via lipid peroxidation. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

Alan Brash

doi:10.1074/jbc.274.34.23679

August 1, 1999Journal of Biological ChemistryOpen Access

Lipoxygenases: Occurrence, Functions, Catalysis, and Acquisition of Substrate

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Key Points

This review aims to explore the diversity of lipoxygenases, their catalytic functions, and the mechanisms of substrate acquisition in various organisms.
Review of literature on lipoxygenases across plants, fungi, and animals
Analysis of enzymatic functions and characteristics
Discussion of substrate acquisition mechanisms in cellular environments
Lipoxygenases are widespread in diverse organisms, with varying expressions and functions.
Different lipoxygenases exhibit unique catalytic mechanisms, influencing signaling and structural changes in cells.
Substrate acquisition is crucial for lipoxygenase activity, with unique characteristics in plants versus animals.

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Implication

Review discusses lipoxygenases' roles, catalytic properties, and substrate acquisition in diverse organisms, indicating functional diversity.

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Alan Brash (1999) studied this question.

synapsesocial.com/papers/6a05429fccdd74096c3457c1 https://doi.org/10.1074/jbc.274.34.23679

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Lipoxygenases: Occurrence, Functions, Catalysis, and Acquisition of Substrate

Key Points

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Lipoxygenases: Occurrence, Functions, Catalysis, and Acquisition of Substrate

Key Points

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Implication

Discussion

Cite This Study

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