What question did this study set out to answer?

This review aims to explore the dual roles of basophils in amplifying and resolving inflammation related to allergies and other inflammatory disorders.

May 14, 2026Allergology InternationalOpen Access

Basophils in the regulation of allergies and inflammatory disorders

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This review aims to explore the dual roles of basophils in amplifying and resolving inflammation related to allergies and other inflammatory disorders.
Comprehensive review of recent genetic models and antibody-based depletion strategies
Analysis of basophil interactions with various immune and non-immune cells
Evaluation of basophil roles in tissue repair and inflammation resolution processes.
Basophils are crucial in amplifying inflammation in allergic conditions like asthma and atopic dermatitis.
They also promote resolution of inflammation by supporting pro-resolving macrophage programs.
Context-dependent roles of basophils include involvement in fibrotic remodeling and lung injury resolution.

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Implication

Review summarizes the impact of basophils on allergic inflammation in atopic dermatitis and asthma, suggesting therapeutic approaches.

Cite This Study

Miyake et al. (2026) studied this question.

synapsesocial.com/papers/6a05659da550a87e60a1dea6 https://doi.org/10.1016/j.alit.2026.04.002

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Basophils in the regulation of allergies and inflammatory disorders

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Discussion

Implication

Cite This Study

Basophils in the regulation of allergies and inflammatory disorders

Key Points

Discussion

Implication

Cite This Study

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