Multi-Stage Surgical Treatment of Penile Squamous Cell Carcinoma: Primary Tumor and Nodal Management Outcomes in a Retrospective Cohort

January 1, 2026ChirurgiaOpen Access

View Full Paper

Ask AI

Bookmark

Share

Key Points

The study aims to evaluate the outcomes and prognostic determinants in patients undergoing multi-stage surgical treatment for penile squamous cell carcinoma.
Retrospective cohort analysis of 49 patients with penile squamous cell carcinoma treated surgically from October 2020 to December 2024.
Patients underwent bilateral inguinal femoral lymphadenectomy after curative resection of the primary tumor.
Overall survival and completion rates of treatment were the main objectives, analyzed using univariate and multivariate Cox regression.
Among 49 patients, 31 (63.3%) completed bilateral lymphadenectomy, while 18 (36.7%) did not comply with treatment.
The overall mortality rate was 55.1% with a median overall survival of 20 months.
Independent prognostic factors for overall survival included absence of lymphovascular invasion (HR 0.43, 95% CI: 0.19-0.99, p=0.048) and absence of urethral invasion (HR 0.36, 95% CI: 0.12-1.03, p=0.056).

Retrospective cohort study demonstrates treatment outcomes in surgical management of penile cancer, suggesting significant prognostic implications.

No abstract yet. The journal hasn't published one we can show.

No takes yet. Share an insight, caveat, or question.

Andreşanu et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark

Share